Dietary intake of energy and fiber in MS patients; an approach to prebiotics role
Abstract
Purpose
Dietary fiber and energy intakes seem to be related to disability and anthropometric indices in multiple sclerosis (MS), a chronic inflammatory disorder of the central nervous system. So, this study was designed to investigate the association between dietary fiber and energy intakes with systemic inflammation, disease severity and anthropometric measurements in MS subjects.
Design/methodology/approach
Four subtypes of 261 MS volunteers were recruited (female = 210, male = 51; mean age 38.9 ± 8.3). A 168-item food frequency questionnaire and nutritionist IV software were used to estimate the amounts of dietary, insoluble, soluble, crude fiber and energy intakes. Serum hs-CRP, extended disability status scale (EDSS), height, weight and Deurenberg equation were also used to evaluate systemic inflammation, disease severity, body mass index (BMI) and percentage body fat, respectively.
Findings
Mean differences among the three hs-CRP and EDSS subgroups for dietary fibers and energy intake were significant (p < 0.001). Dietary fiber intake (M = 19.9 ± 4.3 g/day) was a good predictor for EDSS (B = −0.196, p = 0.012), and insoluble fiber intake was introduced as the best predictor of hs-CRP (B = −3.293, p < 0.001). Energy intake predicted both BMI (B = 0.007, p < 0.001) and percentage body fat (B = 0.015, p < 0.001).
Originality/value
Hypocaloric and high prebiotic fiber diet may suppress systemic inflammation and thereby modulate disease severity, as well as control anthropometric indices.
Keywords
Acknowledgements
The authors thank all the participants and their families and staff of Isfahan MS clinic.
Disclaimer statements: Contributors: study concept and design: Moravejolahkami, Paknahad; sampling and monitor the visiting procedure, EDSS and relapse rate definition: Chitsaz, Moravejolahkami; analysis and interpretation of data: Moravejolahkami; critical review of the manuscript for important intellectual content: Paknahad.
Funding: The authors declare no support from any commercial organization for the submitted study.
Conflicts of interest: None of the authors had a conflict of interest.
Citation
Moravejolahkami, A.R., Paknahad, Z. and Chitsaz, A. (2019), "Dietary intake of energy and fiber in MS patients; an approach to prebiotics role", Nutrition & Food Science, Vol. 49 No. 6, pp. 1039-1050. https://doi.org/10.1108/NFS-01-2019-0001
Publisher
:Emerald Publishing Limited
Copyright © 2019, Emerald Publishing Limited