Rutin alters fatty acid composition in diabetic tissues
Abstract
Purpose
The purpose of this paper is to explore the role of rutin, a polyphenolic flavonoid on the fatty acid composition in liver and kidney of streptozotocin (STZ)‐induced diabetic rats.
Design/methodology/approach
Extensive literature review was carried out and no reports on the effect of rutin on the fatty acid composition in diabetic tissues were found.
Findings
Streptozotocin‐induced diabetic rats showed altered lipid concentration in liver and kidney. The fatty acid composition was also altered in these tissues. Treatment with rutin to diabetic rats significantly decreased the concentration of palmitic acid, stearic acid and oleic acid, whereas linolenic and arachidonic acids were significantly increased in liver and kidney of diabetic rats. Rutin administration to normal rats did not show any significant effect on the fatty acid composition in liver and kidney.
Originality/value
This paper gives an idea of the changes in the fatty acid composition of diabetic tissues and during treatment with rutin.
Keywords
Citation
Kamalakkannan, N. and Alnumair, K.S. (2009), "Rutin alters fatty acid composition in diabetic tissues", Nutrition & Food Science, Vol. 39 No. 6, pp. 655-662. https://doi.org/10.1108/00346650911002986
Publisher
:Emerald Group Publishing Limited
Copyright © 2009, Emerald Group Publishing Limited