A comparison of two diagnostic performance measures: Signal‐to‐noise ratio versus partial area under receiver operating characteristic curve
International Journal of Health Care Quality Assurance
ISSN: 0952-6862
Article publication date: 1 February 2013
Abstract
Purpose
This paper aims to compare two diagnostic performance measures, i.e. signal‐to‐noise ratio (S/N ratio) and partial area under receiver operating characteristic curves (pAUC). It proposes the use of S/N ratio rather than pAUC for establishing optimal cut‐off point for diagnostic biomarkers.
Design/methodology/approach
This paper discusses the properties, uses, advantages and shortcomings of the two performance measures, namely the partial area under receiver operating characteristic curve (pAUC) and Taguchi's signal‐to‐noise (S/N) ratio. The benefits of S/N ratio have been illustrated in a sample of four biomarkers, each having five cut‐off points. The S/N ratio is compared to the pAUC index. The SAS software is employed to calculate pAUC and AUC.
Findings
This paper shows that S/N ratio can be used as a measure of diagnostic accuracy. The cut‐off point with the highest S/N ratio is the optimal cut‐off point for the biomarker. The proposed method has the advantages of being easier, more practical and less costly than that of pAUC.
Practical implications
This paper includes implications for the development of a more practical, equally powerful and less costly means of measuring clinical accuracy thereby reducing the costs and risks resulting from wrong selection of cut‐off point can be decreased.
Originality/value
This paper supports suggestions in the recent literature to replace pAUC with a new, more meaningful index.
Keywords
Citation
Tolga Taner, M., Sezen, B. and Atwat, K. (2013), "A comparison of two diagnostic performance measures: Signal‐to‐noise ratio versus partial area under receiver operating characteristic curve", International Journal of Health Care Quality Assurance, Vol. 26 No. 2, pp. 109-117. https://doi.org/10.1108/09526861311297325
Publisher
:Emerald Group Publishing Limited
Copyright © 2013, Emerald Group Publishing Limited